Patient choice promotes adherence in preventive treatment for latent tuberculosis

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Patient choice promotes adherence in preventive treatment for latent tuberculosis.

The aim of the present study was to compare the effect of patient choice on completion rates and adverse drug reactions for patients treated for latent tuberculosis infection (LTBI) using 3-month rifampicin and isoniazid treatment (3RH) or 6-month isoniazid treatment (6H). Data for all patients treated using 3RH or 6H for LTBI between 1998 and 2004 were analysed. In total, 675 patients attended...

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Factors associated with treatment adherence in a randomised trial of latent tuberculosis infection treatment.

SETTING Randomised controlled trial of latent tuberculosis infection (LTBI) treatment in 10 clinics in Canada, Saudi Arabia and Brazil. OBJECTIVE To identify early predictors of LTBI treatment adherence, including pre-treatment characteristics. DESIGN Patients randomised to 4 months of rifampicin (RMP; n = 420) or 9 months of isoniazid (n = 427) were monitored for adherence using an electro...

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Management of Latent Tuberculosis in Iran

Although screening, finding and treatment of active cases of tuberculosis is very important for control of disease in the community, for reaching to the goals planed by world health organization and approaching to elimination of the disease, it is necessary to find and treat persons with latent infection. Concerning to high prevalence of latent TB in developing countries and resource limitation...

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Interventions for improving adherence to treatment for latent tuberculosis infection: a systematic review

BACKGROUND Latent tuberculosis infection (LTBI) control relies on high initiation and completion rates of preventive treatment to preclude progression to tuberculosis disease. Specific interventions may improve initiation and completion rates. The objective was to systematically review data on determinants of initiation, adherence and completion of LTBI treatment, and on interventions to improv...

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The impact of smoking on adherence to treatment for latent tuberculosis infection

BACKGROUND Studies have shown an association between smoking and tuberculosis (TB) infection, disease and TB-related mortality. We hypothesized that smokers with latent tuberculosis infection (LTBI) are less likely to comply with their LTBI treatment regimen, thus increasing their risk of developing active disease. We thus documented the impact of smoking on adherence to LTBI treatment. METHO...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2007

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.00034007